Rebirth of the God-level Xueba

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"Yang Rui, show me your pipette." Tang concentrated on returning to the laboratory and remembered the words about light weapons and heavy weapons.

Yang Rui returned to the experimental state, and said, "Xiao Sun, give Professor Tang your pipette."

Sun Ruyue is a sophomore this year, and he is one level higher than Yang Rui. At this time, he is called Xiao Sun, but he is holding the pipette out.

Tang concentrated on holding the pipette and looked at it carefully, and asked for a moment: "How much is this pipette?"

"US$600." Sun Ruyue hurriedly said, "Imported from abroad."

"I see." Tang Ji gave Sun Ruyue an angry look, and asked, "Yang Rui, did you buy this yourself?"

"It was bought by Zeneca."

"It doesn't matter if you can use it in our laboratory?"

"I will definitely take it back later, it's useless for the time being." Yang Rui is not going to provide instruments and equipment to Tang's concentrated laboratory. After all, the laboratories concentrated by Tang are also qualified to be selected as national key laboratories. With a yearly funding of millions, buying a few $600 pipettes is nothing, it's just a question of whether he wants it or not.

Yang Rui bought high-priced imported pipettes, on the one hand, because of years of accumulated resentment, on the other hand, the requirements of the experiment, and of course, the most important thing is that he has sufficient funds.

Tang Ji didn't have such a strong demand anymore, so after trying the pipette a few times, he still sighed and said, "It's good, it's expensive."

Sun Ruyue disappointed: "We can't buy it."

"We have a total of 9 people in the laboratory, and it costs 5,400 US dollars to buy 9 pipettes? If the evaluation team sees us spending money like this, they will talk." Tang Ji shook his head and said: "The electrophoresis laboratory is not used yet. For good equipment, Yang Rui can use his own, but you still use the original equipment in the laboratory."

This time even Wang Ying made a tragic cry. It is a very painful thing to use a bad instrument after using a good instrument. The corresponding comparison can be a new computer and an old computer, a smart phone and an analog machine, and most of the fun will be killed by this.

However, scientific research dogs have no right to speak. Tang concentrated on this point, and any wailing is useless.

"From tomorrow onwards, I will keep a pipette." Yang Rui understood what Tang Zhong said.

Tang concentrated on rubbing his head in embarrassment, and said: "It's not that you are not allowed to use it, but I am afraid that the evaluation team will find fault. After this period of time, it will be fine. That's all, let's do our own things."

Dispelling the people, Tang Jiji and Yang Rui talked about the potassium channel protein, saying: "I have to admit, I didn't pay attention to your recent experiment before, because you just published one paper, I thought, you are going to publish the second one." No matter how long it takes two or three months to write a thesis, I didn’t expect it to be so fast.”

"The experiment went well,

I didn't finish all of them, so I published the paper first. "Yang Rui will publish papers as long as there are phased results. This is actually a relatively normal practice. Unless the method is special, for example, the paper has a strange idea and a simple method, otherwise, most laboratories will publish phased results papers For example, China's artificial insulin research, although it was in the 1960s, papers were still published abroad, and more than 20 papers were published successively, which was not easy.

"I see the words "Peking University Electrophoresis Laboratory" on your thesis, which is very good. Let Sun Ruyue follow you in the future and help you. You will also teach him experimental methods and some professional knowledge." Tang Concentrate on giving the youngest scientific research dog to Yang Rui.

Yang Rui published papers in the name of the electrophoresis laboratory. Although the first author is Yang Rui, there is no doubt that both Peking University and the electrophoresis laboratory will be honored, which means that the number of papers under its banner has increased. Although for an institution like Peking University, one or two ordinary papers are insignificant, but for the electrophoresis laboratory, which is competing for a national key laboratory, one more paper is good.

Yang Rui thanked him without hesitation, he really needs an assistant for the experiment now, he can't even wash the bottle by himself, that would be a waste of time. Even though Sun Ruyue had helped him before, after all, his name was not justified.

"If you need help with the next research, you can come to me." Tang Ji clapped his hands and said: "I said before that I would help you apply for school funding, so I will help you fill out an application form tomorrow. Also prepare to see if it can be made into a project, if you pass the application, you will get at least a thousand dollars, what do you think?"

"That's great." Yang Rui entered Tang's concentrated laboratory, in addition to seeking privileges, it was to obtain funding, reputation and corresponding convenience.

Prior to this, Yang Rui paid all his expenses by himself, and the external name was sponsored by Zeneca or Huarui. As a patent project or a profitable medical project, there is no problem with this method, but in a university laboratory, Yang Rui is working on a basic project, and it is a bit unfair to spend his own money.

In the pharmaceutical industry, a new drug usually goes through at least three steps. First, some scholars have completed a basic research, such as potassium channels can affect arrhythmia. After learning about this research, the researchers of the biotechnology company will carry out the second step based on this research, developing or discovering a potassium channel blocker to treat arrhythmia. This blocker can be a brand new The synthetic compound can also be an existing compound. Finally, the third step is to extract or produce this existing compound and carry out standard tests stipulated by various institutions.

Yang Rui's plant extraction method to produce coenzyme Q10 is the third step. The second step before coenzyme Q10 was completed in the early 1970s, and the first basic research was completed in the 1950s.

It is equivalent to saying that it will take 30 years for the drug coenzyme Q10 to be available to consumers.

Among these three steps, the third step is the key to profit, and it is also the most concentrated part of pharmaceutical companies. The second step is already difficult to apply for patents, so only large pharmaceutical companies are involved, hoping to be one step ahead of their opponents.

Most of the research conducted by university laboratories is basic, that is, the first step. They spend a lot of money, but they don’t necessarily know what they will make. Therefore, except for even super pharmaceutical companies, they often only Funding will be sponsored instead of direct investment, and because it is purely basic research, there is no patented scientific research, you cannot apply for a patent for the potassium ion channel of the cell, just like scientists cannot apply for a patent for a newly discovered glacier or organism Same.

However, the force of one, two, and three steps is exactly the opposite of making a profit. The third step, which is the easiest to make a profit, is the lowest, and the first step, which is difficult to make a profit, is the highest.

In terms of difficulty, it can actually be said that the production of drugs to treat cancer is the easiest, and what is used to produce cancer drugs is the most difficult part.

And most of the honors, such as the Nobel Prize, are also awarded to researchers in the first or second step, and rarely to the third step.

Domestic laboratories currently have little funds, but in terms of the whole country, there are actually not many, especially the accumulated instruments and talents will only increase, and there are also advantages in various aspects such as venues and names. There are many places.

The next day, Yang Rui sorted out his resume and wrote down various elements such as the goal of the project application before submitting the funding application under the guidance of Tang Zhong.

Because it is a funding application within the school, the staff in the school office are responsible for accepting it. After reading Yang Rui's application form, he put it in a special kraft paper bag and said: "The school is currently short of funds. Not much, you have to be mentally prepared."

"It's enough to have thousands of dollars." Yang Rui is now doing potassium ion-related experiments, and thousands of dollars are definitely not enough. However, he is currently using the instruments in Tang's concentrated laboratory, and the expenditure is mainly on consumables, which are more or less supplementary.

The staff in the office smiled softly and said, "It's better to think less, and someone will notify you when the application is approved."

"Okay." Yang Rui's psychological expectations dropped instantly.

Tang Jiji said consolingly: "This is the first time you are applying for a project. It is good if you can be approved. As long as you have results and pass the inspection, the next application will be easy. Besides, you can also apply for projects in Beijing and the country. Those are the big bucks."

"I understand." Yang Rui recalled his postgraduate days running projects with his tutor, and thought: Although they are different, the essence is indeed the same.